Soluble Expression of hFGF19 without Fusion Protein through Synonymous Codon Substitutions and DsbC Co-Expression in E. coli

Human fibroblast growth factor 19 (hFGF19) is a difficult-to-express protein that is frequently fused with another protein for soluble expression. However, residual amino acids after cleavage with protease represent one of the major problems in therapeutic protein development. Here, we introduced sy...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Hye-Ji, Cheong, Dae-Eun, Yoo, Su-Kyoung, Park, Jaehong, Lee, Dong-Hyun, Kim, Geun-Joong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762406/
https://www.ncbi.nlm.nih.gov/pubmed/33297586
http://dx.doi.org/10.3390/microorganisms8121942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762406/
https://www.ncbi.nlm.nih.gov/pubmed/33297586
http://dx.doi.org/10.3390/microorganisms8121942

Ejemplares similares