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Autophagy in Osteosarcoma Cancer Stem Cells Is a Critical Process which Can Be Targeted by the Antipsychotic Drug Thioridazine

SIMPLE SUMMARY: Cancer stem cells (CSCs) represent a minor population of cancer cells with stem cell-like properties and appear as a crucial target in oncology as they are the origin of relapses and resistance to current treatments. Autophagy, which allows the degradation and recycling of cellular c...

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Detalles Bibliográficos
Autores principales: Camuzard, Olivier, Trojani, Marie-Charlotte, Santucci-Darmanin, Sabine, Pagnotta, Sophie, Breuil, Véronique, Carle, Georges F., Pierrefite-Carle, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762415/
https://www.ncbi.nlm.nih.gov/pubmed/33297525
http://dx.doi.org/10.3390/cancers12123675