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Extracellular vesicle derived miR-544 downregulates expression of tumor suppressor promyelocytic leukemia zinc finger resulting in increased peritoneal metastasis in gastric cancer

Peritoneal metastasis (PM) is the main cause of poor prognosis in patients with advanced gastric cancer (GC). Increasing evidence has suggested that cancer-associated EVs in body fluids may assist in the diagnosis and treatment of GC. Here, we investigated the role of GC-derived EVs in PM developmen...

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Detalles Bibliográficos
Autores principales: Kong, Wencheng, Liu, Xinchun, Yin, Guang, Zheng, Sixin, Zhu, Akao, Yu, Panpan, Shan, Yuqiang, Ying, Rongchao, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762464/
https://www.ncbi.nlm.nih.gov/pubmed/33221764
http://dx.doi.org/10.18632/aging.104082