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FOXO3 longevity genotype mitigates the increased mortality risk in men with a cardiometabolic disease

FOXO3 is a prominent longevity gene. To date, no-one has examined whether longevity-associated FOXO3 genetic variants protect against mortality in all individuals, or only in those with aging-related diseases. We therefore tested longevity-associated FOXO3 single nucleotide polymorphisms in a haplot...

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Detalles Bibliográficos
Autores principales: Chen, Randi, Morris, Brian J., Donlon, Timothy A., Masaki, Kamal H., Willcox, D. Craig, Davy, Philip M.C., Allsopp, Richard C., Willcox, Bradley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762472/
https://www.ncbi.nlm.nih.gov/pubmed/33260156
http://dx.doi.org/10.18632/aging.202175