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Transforming growth factor beta type 1 (TGF-β) and hypoxia-inducible factor 1 (HIF-1) transcription complex as master regulators of the immunosuppressive protein galectin-9 expression in human cancer and embryonic cells

Galectin-9 is one of the key proteins employed by a variety of human malignancies to suppress anti-cancer activities of cytotoxic lymphoid cells and thus escape immune surveillance. Human cancer cells in most cases express higher levels of galectin-9 compared to non-transformed cells. However, the b...

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Detalles Bibliográficos
Autores principales: Selnø, Anette Teo Hansen, Schlichtner, Stephanie, Yasinska, Inna M., Sakhnevych, Svetlana S., Fiedler, Walter, Wellbrock, Jasmin, Klenova, Elena, Pavlova, Ludmila, Gibbs, Bernhard F., Degen, Martin, Schnyder, Isabelle, Aliu, Nijas, Berger, Steffen M., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762483/
https://www.ncbi.nlm.nih.gov/pubmed/33295886
http://dx.doi.org/10.18632/aging.202343