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Effect of lncRNA WT1-AS regulating WT1 on oxidative stress injury and apoptosis of neurons in Alzheimer's disease via inhibition of the miR-375/SIX4 axis

Objective: To study the effect of lncRNA WT1-AS on oxidative stress injury (OSI) and apoptosis of neurons in Alzheimer's disease (AD) and its specific mechanisms related to the microRNA-375 (miR-375)/SIX4 axis and WT1 expression. Results: After bioinformatic prediction, WT1-AS was found to be d...

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Detalles Bibliográficos
Autores principales: Wang, Quanbao, Ge, Xiumin, Zhang, Jie, Chen, Licheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762490/
https://www.ncbi.nlm.nih.gov/pubmed/33234729
http://dx.doi.org/10.18632/aging.104079