Hypoxia induces pulmonary artery smooth muscle dysfunction through mitochondrial fragmentation-mediated endoplasmic reticulum stress

Pulmonary arterial hypertension (PAH) is characterized by pulmonary artery smooth muscle cell (PASMC) dysfunction. However, the underlying mechanisms of PASMC dysfunction remain largely unknown. Here, we show that mitochondrial fragmentation contributes to PASMC dysfunction through enhancement of en...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhuan, Bing, Wang, Xi, Wang, Ming-Deng, Li, Zhi-Cai, Yuan, Qun, Xie, Jun, Yang, Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762493/
https://www.ncbi.nlm.nih.gov/pubmed/33221740
http://dx.doi.org/10.18632/aging.103892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762493/
https://www.ncbi.nlm.nih.gov/pubmed/33221740
http://dx.doi.org/10.18632/aging.103892

Ejemplares similares