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DNMT3B silencing suppresses migration and invasion by epigenetically promoting miR-34a in bladder cancer

The role of DNA methyltransferase 3B (DNMT3B) in tumorigenesis and development has been widely recognized; however, the mechanism underlying its action remains unclear. Considering its function in de novo methylation, we aimed to investigate whether DNMT3B plays its role via microRNA (miR)-34a promo...

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Detalles Bibliográficos
Autores principales: Xu, Kai, Chen, Binshen, Li, Bingkun, Li, Chaoming, Zhang, Yiming, Jiang, Ning, Lang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762500/
https://www.ncbi.nlm.nih.gov/pubmed/33221743
http://dx.doi.org/10.18632/aging.103820