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Cigarette smoke extract induces airway epithelial cell death via repressing PRMT6/AKT signaling

Chronic obstructive pulmonary disease (COPD) is a severe public health threat world-wide. Cigarette smoke (CS)-induced airway epithelial cell death is a major pathway of pathogenesis in emphysema, a subtype of COPD. Protein arginine methyltransferase 6 (PRMT6) is a type I PRMT that catalyzes mono- a...

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Detalles Bibliográficos
Autores principales: Li, Tiao, Fanning, Kristen V., Nyunoya, Toru, Chen, Yan, Zou, Chunbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762507/
https://www.ncbi.nlm.nih.gov/pubmed/33260152
http://dx.doi.org/10.18632/aging.202210