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Polypeptide-Based Molecular Platform and Its Docetaxel/Sulfo-Cy5-Containing Conjugate for Targeted Delivery to Prostate Specific Membrane Antigen

A strategy for stereoselective synthesis of molecular platform for targeted delivery of bimodal therapeutic or theranostic agents to the prostate-specific membrane antigen (PSMA) receptor was developed. The proposed platform contains a urea-based, PSMA-targeting Glu-Urea-Lys (EuK) fragment as a vect...

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Detalles Bibliográficos
Autores principales: Petrov, Stanislav A., Machulkin, Aleksei E., Uspenskaya, Anastasia A., Zyk, Nikolay Y., Nimenko, Ekaterina A., Garanina, Anastasia S., Petrov, Rostislav A., Polshakov, Vladimir I., Grishin, Yuri K., Roznyatovsky, Vitaly A., Zyk, Nikolay V., Majouga, Alexander G., Beloglazkina, Elena K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762530/
https://www.ncbi.nlm.nih.gov/pubmed/33302417
http://dx.doi.org/10.3390/molecules25245784