Genomic Analysis of Natural Rough Brucella melitensis Rev.1 Vaccine Strains: Identification and Characterization of Mutations in Key Genes Associated with Bacterial LPS Biosynthesis and Virulence

Brucella species are facultative intracellular bacteria that cause brucellosis, a zoonotic world-wide disease. The live attenuated B. melitensis Rev.1 vaccine strain is widely used for the control of brucellosis in the small ruminant population. However, Rev.1 induces antibodies against the O-polysa...

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Detalles Bibliográficos
Autores principales: Kornspan, David, Lubkovskaia, Regina, Mathur, Shubham, Yeheskel, Adva, Salmon-Divon, Mali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762576/
https://www.ncbi.nlm.nih.gov/pubmed/33302421
http://dx.doi.org/10.3390/ijms21249341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762576/
https://www.ncbi.nlm.nih.gov/pubmed/33302421
http://dx.doi.org/10.3390/ijms21249341

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