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Genomic Analysis of Natural Rough Brucella melitensis Rev.1 Vaccine Strains: Identification and Characterization of Mutations in Key Genes Associated with Bacterial LPS Biosynthesis and Virulence
Brucella species are facultative intracellular bacteria that cause brucellosis, a zoonotic world-wide disease. The live attenuated B. melitensis Rev.1 vaccine strain is widely used for the control of brucellosis in the small ruminant population. However, Rev.1 induces antibodies against the O-polysa...
Autores principales: | Kornspan, David, Lubkovskaia, Regina, Mathur, Shubham, Yeheskel, Adva, Salmon-Divon, Mali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762576/ https://www.ncbi.nlm.nih.gov/pubmed/33302421 http://dx.doi.org/10.3390/ijms21249341 |
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