Aberrant Activity of Histone–Lysine N-Methyltransferase 2 (KMT2) Complexes in Oncogenesis

KMT2 (histone-lysine N-methyltransferase subclass 2) complexes methylate lysine 4 on the histone H3 tail at gene promoters and gene enhancers and, thus, control the process of gene transcription. These complexes not only play an essential role in normal development but have also been described as in...

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Detalles Bibliográficos
Autores principales: Poreba, Elzbieta, Lesniewicz, Krzysztof, Durzynska, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762615/
https://www.ncbi.nlm.nih.gov/pubmed/33302406
http://dx.doi.org/10.3390/ijms21249340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762615/
https://www.ncbi.nlm.nih.gov/pubmed/33302406
http://dx.doi.org/10.3390/ijms21249340

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