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Double-Hit Primary Plasma Cell Leukemia with IGH/MYC and IGH/CCND1 Translocations
Primary plasma cell leukemia (pPCL) is an aggressive variant of multiple myeloma (MM). Immunoglobulin heavy chain (IgH) translocations are found in a majority of pPCL cases, supporting a central relation to pathogenesis of pPCL. However, two independent IgH translocations are barely detected at the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762630/ https://www.ncbi.nlm.nih.gov/pubmed/33381329 http://dx.doi.org/10.1155/2020/8811114 |