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Double-Hit Primary Plasma Cell Leukemia with IGH/MYC and IGH/CCND1 Translocations

Primary plasma cell leukemia (pPCL) is an aggressive variant of multiple myeloma (MM). Immunoglobulin heavy chain (IgH) translocations are found in a majority of pPCL cases, supporting a central relation to pathogenesis of pPCL. However, two independent IgH translocations are barely detected at the...

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Detalles Bibliográficos
Autores principales: Yasumi, Masato, Endo, Takaya, Sata, Hiroshi, Karasuno, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762630/
https://www.ncbi.nlm.nih.gov/pubmed/33381329
http://dx.doi.org/10.1155/2020/8811114