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Hyperbranched Cationic Glycogen Derivative-Mediated IκBα Gene Silencing Regulates the Uveoscleral Outflow Pathway in Rats

The role of the IκB/NF-κB signaling pathway in the uveoscleral outflow pathway was investigated with IκBα gene silencing mediated by the 3-(dimethylamino)-1-propylamine-conjugated glycogen (DMAPA-Glyp) derivative. The IκBα-siRNA-loaded DMAPA-Glyp complex was transfected into the ciliary muscles of r...

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Detalles Bibliográficos
Autores principales: Zeng, Rui, Li, Jinmiao, Gong, Haijun, Luo, Jiahao, Li, Zijing, Ou, Zhaoxing, Zhang, Si, Yang, Liqun, Lan, Yuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762656/
https://www.ncbi.nlm.nih.gov/pubmed/33381584
http://dx.doi.org/10.1155/2020/8206849