Kindlin-2 regulates skeletal homeostasis by modulating PTH1R in mice

In vertebrates, the type 1 parathyroid hormone receptor (PTH1R) is a critical regulator of skeletal development and homeostasis; however, how it is modulated is incompletely understood. Here we report that deleting Kindlin-2 in osteoblastic cells using the mouse 10-kb Dmp1-Cre largely neutralizes th...

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Detalles Bibliográficos
Autores principales: Fu, Xuekun, Zhou, Bo, Yan, Qinnan, Tao, Chu, Qin, Lei, Wu, Xiaohao, Lin, Sixiong, Chen, Sheng, Lai, Yumei, Zou, Xuenong, Shao, Zengwu, Wang, Meiqing, Chen, Di, Jin, Wenfei, Song, Youqiang, Cao, Huiling, Zhang, Ge, Xiao, Guozhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762753/
https://www.ncbi.nlm.nih.gov/pubmed/33361757
http://dx.doi.org/10.1038/s41392-020-00328-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762753/
https://www.ncbi.nlm.nih.gov/pubmed/33361757
http://dx.doi.org/10.1038/s41392-020-00328-y

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