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Epothilones Improve Axonal Growth and Motor Outcomes after Stroke in the Adult Mammalian CNS

Stroke leads to the degeneration of short-range and long-range axonal connections emanating from peri-infarct tissue, but it also induces novel axonal projections. However, this regeneration is hampered by growth-inhibitory properties of peri-infarct tissue and fibrotic scarring. Here, we tested the...

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Detalles Bibliográficos
Autores principales: Kugler, Christof, Thielscher, Christian, Tambe, Bertrand A., Schwarz, Martin K., Halle, Annett, Bradke, Frank, Petzold, Gabor C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762779/
https://www.ncbi.nlm.nih.gov/pubmed/33377130
http://dx.doi.org/10.1016/j.xcrm.2020.100159