Physiologically‐Based Pharmacokinetic Modelling of Creatinine‐Drug Interactions in the Chronic Kidney Disease Population

Elevated serum creatinine (S(Cr)) caused by the inhibition of renal transporter(s) may be misinterpreted as kidney injury. The interpretation is more complicated in patients with chronic kidney disease (CKD) due to altered disposition of creatinine and renal transporter inhibitors. A clinical study...

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Detalles Bibliográficos
Autores principales: Takita, Hiroyuki, Scotcher, Daniel, Chinnadurai, Rajkumar, Kalra, Philip A., Galetin, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762809/
https://www.ncbi.nlm.nih.gov/pubmed/33049120
http://dx.doi.org/10.1002/psp4.12566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762809/
https://www.ncbi.nlm.nih.gov/pubmed/33049120
http://dx.doi.org/10.1002/psp4.12566

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