Directly imaging the localisation and photosensitization properties of the pan-mTOR inhibitor, AZD2014, in living cancer cells()

The range of cellular functions the mechanistic target of rapamycin (mTOR) protein performs makes it an attractive drug target for cancer therapy. However, the cellular localisation and mode of action of second generation inhibitors of mTOR is poorly understood despite the level of attention there i...

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Detalles Bibliográficos
Autores principales: Ahmed, Abdullah R., Candeo, Alessia, D'Abrantes, Sofia, Needham, Sarah R., Yadav, Rahul B., Botchway, Stanley W., Parker, Anthony W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Sequoia 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762844/
https://www.ncbi.nlm.nih.gov/pubmed/33142217
http://dx.doi.org/10.1016/j.jphotobiol.2020.112055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762844/
https://www.ncbi.nlm.nih.gov/pubmed/33142217
http://dx.doi.org/10.1016/j.jphotobiol.2020.112055

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