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AggreCount: an unbiased image analysis tool for identifying and quantifying cellular aggregates in a spatially defined manner
Protein quality control is maintained by a number of integrated cellular pathways that monitor the folding and functionality of the cellular proteome. Defects in these pathways lead to the accumulation of misfolded or faulty proteins that may become insoluble and aggregate over time. Protein aggrega...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762942/ https://www.ncbi.nlm.nih.gov/pubmed/33454006 http://dx.doi.org/10.1074/jbc.RA120.015398 |