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AggreCount: an unbiased image analysis tool for identifying and quantifying cellular aggregates in a spatially defined manner

Protein quality control is maintained by a number of integrated cellular pathways that monitor the folding and functionality of the cellular proteome. Defects in these pathways lead to the accumulation of misfolded or faulty proteins that may become insoluble and aggregate over time. Protein aggrega...

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Detalles Bibliográficos
Autores principales: Klickstein, Jacob Aaron, Mukkavalli, Sirisha, Raman, Malavika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762942/
https://www.ncbi.nlm.nih.gov/pubmed/33454006
http://dx.doi.org/10.1074/jbc.RA120.015398