Mycobacterium tuberculosis infection up-regulates MFN2 expression to promote NLRP3 inflammasome formation

Tuberculosis (TB), caused by the infection of Mycobacterium tuberculosis (MTB), is one of the leading causes of death worldwide, especially in children. However, the mechanisms by which MTB infects its cellular host, activates an immune response, and triggers inflammation remain unknown. Mitochondri...

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Detalles Bibliográficos
Autores principales: Xu, Fang, Qi, Hui, Li, Jieqiong, Sun, Lin, Gong, Juanjuan, Chen, Yuanying, Shen, Adong, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762945/
https://www.ncbi.nlm.nih.gov/pubmed/33454007
http://dx.doi.org/10.1074/jbc.RA120.014077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762945/
https://www.ncbi.nlm.nih.gov/pubmed/33454007
http://dx.doi.org/10.1074/jbc.RA120.014077

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