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N-acetylglucosamine drives myelination by triggering oligodendrocyte precursor cell differentiation

Myelination plays an important role in cognitive development and in demyelinating diseases like multiple sclerosis (MS), where failure of remyelination promotes permanent neuro-axonal damage. Modification of cell surface receptors with branched N-glycans coordinates cell growth and differentiation b...

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Detalles Bibliográficos
Autores principales: Sy, Michael, Brandt, Alexander U., Lee, Sung-Uk, Newton, Barbara L., Pawling, Judy, Golzar, Autreen, Rahman, Anas M. A., Yu, Zhaoxia, Cooper, Graham, Scheel, Michael, Paul, Friedemann, Dennis, James W., Demetriou, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762951/
https://www.ncbi.nlm.nih.gov/pubmed/33453988
http://dx.doi.org/10.1074/jbc.RA120.015595