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N-acetylglucosamine drives myelination by triggering oligodendrocyte precursor cell differentiation
Myelination plays an important role in cognitive development and in demyelinating diseases like multiple sclerosis (MS), where failure of remyelination promotes permanent neuro-axonal damage. Modification of cell surface receptors with branched N-glycans coordinates cell growth and differentiation b...
Autores principales: | Sy, Michael, Brandt, Alexander U., Lee, Sung-Uk, Newton, Barbara L., Pawling, Judy, Golzar, Autreen, Rahman, Anas M. A., Yu, Zhaoxia, Cooper, Graham, Scheel, Michael, Paul, Friedemann, Dennis, James W., Demetriou, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762951/ https://www.ncbi.nlm.nih.gov/pubmed/33453988 http://dx.doi.org/10.1074/jbc.RA120.015595 |
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