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Design, Preparation, and Evaluation of a Novel (99m)TcN Complex of Ciprofloxacin Xanthate as a Potential Bacterial Infection Imaging Agent

In order to seek novel technetium-99m bacterial infection imaging agents, a ciprofloxacin xanthate (CPF2XT) was synthesized and radiolabeled with [(99m)TcN](2+) core to obtain the (99m)TcN-CPF2XT complex, which exhibited high radiochemical purity, hydrophilicity, and good stability in vitro. The bac...

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Detalles Bibliográficos
Autores principales: Fang, Si’an, Jiang, Yuhao, Gan, Qianqian, Ruan, Qing, Xiao, Di, Zhang, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762968/
https://www.ncbi.nlm.nih.gov/pubmed/33322004
http://dx.doi.org/10.3390/molecules25245837