Serine Racemase Deletion Affects the Excitatory/Inhibitory Balance of the Hippocampal CA1 Network

d-serine is the major co-agonist of N-methyl-D-aspartate receptors (NMDAR) at CA3/CA1 hippocampal synapses, the activation of which drives long-term potentiation (LTP). The use of mice with targeted deletion of the serine racemase (SR) enzyme has been an important tool to uncover the physiological a...

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Detalles Bibliográficos
Autores principales: Ploux, Eva, Bouet, Valentine, Radzishevsky, Inna, Wolosker, Herman, Freret, Thomas, Billard, Jean-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763099/
https://www.ncbi.nlm.nih.gov/pubmed/33322577
http://dx.doi.org/10.3390/ijms21249447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763099/
https://www.ncbi.nlm.nih.gov/pubmed/33322577
http://dx.doi.org/10.3390/ijms21249447

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