Cargando…
Serine Racemase Deletion Affects the Excitatory/Inhibitory Balance of the Hippocampal CA1 Network
d-serine is the major co-agonist of N-methyl-D-aspartate receptors (NMDAR) at CA3/CA1 hippocampal synapses, the activation of which drives long-term potentiation (LTP). The use of mice with targeted deletion of the serine racemase (SR) enzyme has been an important tool to uncover the physiological a...
Autores principales: | Ploux, Eva, Bouet, Valentine, Radzishevsky, Inna, Wolosker, Herman, Freret, Thomas, Billard, Jean-Marie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763099/ https://www.ncbi.nlm.nih.gov/pubmed/33322577 http://dx.doi.org/10.3390/ijms21249447 |
Ejemplares similares
-
Functional Dysregulations in CA1 Hippocampal Networks of a 3-Hit Mouse Model of Schizophrenia
por: Percelay, Solenn, et al.
Publicado: (2021) -
5-HT6 Receptors Sex-Dependently Modulate Hippocampal Synaptic Activity through GABA Inhibition
por: Lahogue, Caroline, et al.
Publicado: (2023) -
d-serine availability modulates prefrontal cortex inhibitory interneuron development and circuit maturation
por: Folorunso, Oluwarotimi O., et al.
Publicado: (2023) -
Serine racemase deletion attenuates neurodegeneration and microvascular damage in diabetic retinopathy
por: Ozaki, Hironori, et al.
Publicado: (2018) -
Changes in Serine Racemase-Dependent Modulation of NMDA Receptor: Impact on Physiological and Pathological Brain Aging
por: Billard, Jean-Marie
Publicado: (2018)