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Design and Characterisation of Inhibitory Peptides against Bleg1_2478, an Evolutionary Divergent B3 Metallo-β-lactamase

Previously, a hypothetical protein (HP) termed Bleg1_2437 (currently named Bleg1_2478) from Bacillus lehensis G1 was discovered to be an evolutionary divergent B3 subclass metallo-β-lactamase (MBL). Due to the scarcity of clinical inhibitors for B3 MBLs and the divergent nature of Bleg1_2478, this s...

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Detalles Bibliográficos
Autores principales: Selvaraju, Gayathri, Leow, Thean Chor, Salleh, Abu Bakar, Normi, Yahaya M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763155/
https://www.ncbi.nlm.nih.gov/pubmed/33316879
http://dx.doi.org/10.3390/molecules25245797