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Citrate Supplementation Restores the Impaired Mineralisation Resulting from the Acidic Microenvironment: An In Vitro Study

Chronic metabolic acidosis leads to bone-remodelling disorders based on excessive mineral matrix resorption and inhibition of bone formation, but also affects the homeostasis of citrate, which is an essential player in maintaining the acid–base balance and in driving the mineralisation process. This...

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Detalles Bibliográficos
Autores principales: Perut, Francesca, Graziani, Gabriela, Columbaro, Marta, Caudarella, Renata, Baldini, Nicola, Granchi, Donatella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763163/
https://www.ncbi.nlm.nih.gov/pubmed/33317151
http://dx.doi.org/10.3390/nu12123779