SoupX removes ambient RNA contamination from droplet-based single-cell RNA sequencing data

BACKGROUND: Droplet-based single-cell RNA sequence analyses assume that all acquired RNAs are endogenous to cells. However, any cell-free RNAs contained within the input solution are also captured by these assays. This sequencing of cell-free RNA constitutes a background contamination that confounds...

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Detalles Bibliográficos
Autores principales: Young, Matthew D, Behjati, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763177/
https://www.ncbi.nlm.nih.gov/pubmed/33367645
http://dx.doi.org/10.1093/gigascience/giaa151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763177/
https://www.ncbi.nlm.nih.gov/pubmed/33367645
http://dx.doi.org/10.1093/gigascience/giaa151

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