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SoupX removes ambient RNA contamination from droplet-based single-cell RNA sequencing data
BACKGROUND: Droplet-based single-cell RNA sequence analyses assume that all acquired RNAs are endogenous to cells. However, any cell-free RNAs contained within the input solution are also captured by these assays. This sequencing of cell-free RNA constitutes a background contamination that confounds...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763177/ https://www.ncbi.nlm.nih.gov/pubmed/33367645 http://dx.doi.org/10.1093/gigascience/giaa151 |