Galeon: A Biologically Active Molecule with In Silico Metabolite Prediction, In Vitro Metabolic Profiling in Rat Liver Microsomes, and In Silico Binding Mechanisms with CYP450 Isoforms

Galeon, a natural cyclic-diarylheptanoid (CDH), which was first isolated from Myrica gale L., is known to have potent cytotoxicity against A549 cell lines, anti-tubercular activity against Mycobacterium tuberculosis H37Rv, chemo-preventive potential, and moderate topoisomerase inhibitory activity. H...

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Detalles Bibliográficos
Autores principales: Rahman, A. F. M. Motiur, Yin, Wencui, Kadi, Adnan A., Jahng, Yurngdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763192/
https://www.ncbi.nlm.nih.gov/pubmed/33322201
http://dx.doi.org/10.3390/molecules25245903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763192/
https://www.ncbi.nlm.nih.gov/pubmed/33322201
http://dx.doi.org/10.3390/molecules25245903

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