Parameters for Irreversible Inactivation of Monoamine Oxidase

The irreversible inhibitors of monoamine oxidases (MAO) slow neurotransmitter metabolism in depression and neurodegenerative diseases. After oxidation by MAO, hydrazines, cyclopropylamines and propargylamines form a covalent adduct with the flavin cofactor. To assist the design of new compounds to c...

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Detalles Bibliográficos
Autores principales: Ramsay, Rona R., Basile, Livia, Maniquet, Antonin, Hagenow, Stefanie, Pappalardo, Matteo, Saija, Maria Chiara, Bryant, Sharon D., Albreht, Alen, Guccione, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763263/
https://www.ncbi.nlm.nih.gov/pubmed/33322203
http://dx.doi.org/10.3390/molecules25245908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763263/
https://www.ncbi.nlm.nih.gov/pubmed/33322203
http://dx.doi.org/10.3390/molecules25245908

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