Implications of Metastable Nicks and Nicked Holliday Junctions in Processing Joint Molecules in Mitosis and Meiosis

Joint molecules (JMs) are intermediates of homologous recombination (HR). JMs rejoin sister or homolog chromosomes and must be removed timely to allow segregation in anaphase. Current models pinpoint Holliday junctions (HJs) as a central JM. The canonical HJ (cHJ) is a four-way DNA that needs specia...

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Detalles Bibliográficos
Autor principal: Machín, Félix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Concept Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763299/
https://www.ncbi.nlm.nih.gov/pubmed/33322845
http://dx.doi.org/10.3390/genes11121498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763299/
https://www.ncbi.nlm.nih.gov/pubmed/33322845
http://dx.doi.org/10.3390/genes11121498

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