t(8;21) Acute Myeloid Leukemia as a Paradigm for the Understanding of Leukemogenesis at the Level of Gene Regulation and Chromatin Programming

Acute myeloid leukemia (AML) is a heterogenous disease with multiple sub-types which are defined by different somatic mutations that cause blood cell differentiation to go astray. Mutations occur in genes encoding members of the cellular machinery controlling transcription and chromatin structure, i...

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Detalles Bibliográficos
Autores principales: Kellaway, Sophie, Chin, Paulynn S., Barneh, Farnaz, Bonifer, Constanze, Heidenreich, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763303/
https://www.ncbi.nlm.nih.gov/pubmed/33322186
http://dx.doi.org/10.3390/cells9122681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763303/
https://www.ncbi.nlm.nih.gov/pubmed/33322186
http://dx.doi.org/10.3390/cells9122681

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