Androgens Accentuate TGF‐β Dependent Erk/Smad Activation During Thoracic Aortic Aneurysm Formation in Marfan Syndrome Male Mice

BACKGROUND: Male patients with Marfan syndrome have a higher risk of aortic events and root dilatation compared with females. The role androgens play during Marfan syndrome aneurysm development in males remains unknown. We hypothesized that androgens potentiate transforming growth factor beta induce...

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Detalles Bibliográficos
Autores principales: Tashima, Yasushi, He, Hao, Cui, Jason Z., Pedroza, Albert J., Nakamura, Ken, Yokoyama, Nobu, Iosef, Cristiana, Burdon, Grayson, Koyano, Tiffany, Yamaguchi, Atsushi, Fischbein, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763370/
https://www.ncbi.nlm.nih.gov/pubmed/33059492
http://dx.doi.org/10.1161/JAHA.119.015773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763370/
https://www.ncbi.nlm.nih.gov/pubmed/33059492
http://dx.doi.org/10.1161/JAHA.119.015773

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