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The PKGIα/VASP pathway is involved in insulin- and high glucose-dependent regulation of albumin permeability in cultured rat podocytes

Podocytes, the principal component of the glomerular filtration barrier, regulate glomerular permeability to albumin via their contractile properties. Both insulin- and high glucose (HG)-dependent activation of protein kinase G type Iα (PKGIα) cause reorganization of the actin cytoskeleton and podoc...

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Detalles Bibliográficos
Autores principales: Rachubik, Patrycja, Szrejder, Maria, Audzeyenka, Irena, Rogacka, Dorota, Rychłowski, Michał, Angielski, Stefan, Piwkowska, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763511/
https://www.ncbi.nlm.nih.gov/pubmed/32484874
http://dx.doi.org/10.1093/jb/mvaa059