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An Alternative HIV-1 Non-Nucleoside Reverse Transcriptase Inhibition Mechanism: Targeting the p51 Subunit

The ongoing development of drug resistance in HIV continues to push for the need of alternative drug targets in inhibiting HIV. One such target is the Reverse transcriptase (RT) enzyme which is unique and critical in the viral life cycle—a rational target that is likely to have less off-target effec...

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Detalles Bibliográficos
Autores principales: Chan, Kwok-Fong, Su, Chinh Tran-To, Krah, Alexander, Phua, Ser-Xian, Yeo, Joshua Yi, Ling, Wei-Li, Bond, Peter J., Gan, Samuel Ken-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763519/
https://www.ncbi.nlm.nih.gov/pubmed/33322154
http://dx.doi.org/10.3390/molecules25245902