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The CCR2/MCP-1 Chemokine Pathway and Lung Adenocarcinoma

SIMPLE SUMMARY: Myeloid-derived suppressor cells (MDSCs) are present at the sites of many solid tumors and dampen host immune responses. We studied how these MDSCs accumulate and how this process might be interrupted using lung cancer cell lines growing in immunocompetent mice. We found that tumor c...

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Detalles Bibliográficos
Autores principales: Mittal, Payal, Wang, Liqing, Akimova, Tatiana, Leach, Craig A., Clemente, Jose C., Sender, Matthew R., Chen, Yao, Turunen, Brandon J., Hancock, Wayne W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763565/
https://www.ncbi.nlm.nih.gov/pubmed/33322474
http://dx.doi.org/10.3390/cancers12123723