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β-Naphthoflavone Activation of the Ah Receptor Alleviates Irradiation-Induced Intestinal Injury in Mice

Radiotherapy induced gastrointestinal syndrome results from the acute damage of intestinal stem cells, impaired crypts reconstruction, and subsequent breakdown of the mucosal barrier. The toxicity of ionizing radiation is associated with oxidative stress in the intestinal epithelial cells (IECs). Mo...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaoliang, Li, Deguan, Xu, Wenqing, Zhang, Heng, Wang, Hao, Perdew, Gary H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763649/
https://www.ncbi.nlm.nih.gov/pubmed/33322705
http://dx.doi.org/10.3390/antiox9121264