Grindstone Chemistry: Design, One-Pot Synthesis, and Promising Anticancer Activity of Spiro[acridine-9,2′-indoline]-1,3,8-trione Derivatives against the MCF-7 Cancer Cell Line

In this study, the synthesis of one-pot 10-phenyl-3,4,6,7-tetrahydro-1H-spiro [acridine-9,2′-indoline]-1,3,8-trione derivatives was achieved via a four-component cyclocondensation reaction, which was carried out in solvent-free conditions, and using p-toluenesulfonic acid (p-TSA) as a catalyst. The...

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Detalles Bibliográficos
Autores principales: Gobinath, Perumal, Packialakshmi, Ponnusamy, Daoud, Ali, Alarifi, Saud, Idhayadhulla, Akbar, Radhakrishnan, Surendrakumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763815/
https://www.ncbi.nlm.nih.gov/pubmed/33322433
http://dx.doi.org/10.3390/molecules25245862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763815/
https://www.ncbi.nlm.nih.gov/pubmed/33322433
http://dx.doi.org/10.3390/molecules25245862

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