Notable Underlying Mechanism for Pancreatic β-Cell Dysfunction and Atherosclerosis: Pleiotropic Roles of Incretin and Insulin Signaling

Under healthy conditions, pancreatic β-cells produce and secrete the insulin hormone in response to blood glucose levels. Under diabetic conditions, however, β-cells are compelled to continuously secrete larger amounts of insulin to reduce blood glucose levels, and thereby, the β-cell function is de...

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Detalles Bibliográficos
Autores principales: Kaneto, Hideaki, Obata, Atsushi, Kimura, Tomohiko, Shimoda, Masashi, Sanada, Junpei, Fushimi, Yoshiro, Katakami, Naoto, Matsuoka, Takaaki, Kaku, Kohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763860/
https://www.ncbi.nlm.nih.gov/pubmed/33322512
http://dx.doi.org/10.3390/ijms21249444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763860/
https://www.ncbi.nlm.nih.gov/pubmed/33322512
http://dx.doi.org/10.3390/ijms21249444

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