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Notable Underlying Mechanism for Pancreatic β-Cell Dysfunction and Atherosclerosis: Pleiotropic Roles of Incretin and Insulin Signaling
Under healthy conditions, pancreatic β-cells produce and secrete the insulin hormone in response to blood glucose levels. Under diabetic conditions, however, β-cells are compelled to continuously secrete larger amounts of insulin to reduce blood glucose levels, and thereby, the β-cell function is de...
Autores principales: | Kaneto, Hideaki, Obata, Atsushi, Kimura, Tomohiko, Shimoda, Masashi, Sanada, Junpei, Fushimi, Yoshiro, Katakami, Naoto, Matsuoka, Takaaki, Kaku, Kohei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763860/ https://www.ncbi.nlm.nih.gov/pubmed/33322512 http://dx.doi.org/10.3390/ijms21249444 |
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