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Role of Hypoxia and the Adenosine System in Immune Evasion and Prognosis of Patients with Brain Metastases of Melanoma: A Multiplex Whole Slide Immunofluorescence Study

SIMPLE SUMMARY: The introduction of immune-checkpoint inhibitors improved the therapeutic landscape for patients with advanced malignant melanoma. However, many patients, including patients with melanoma brain metastases, do not derive benefit from immune-checkpoint blockade. Hence, biomarkers are n...

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Detalles Bibliográficos
Autores principales: Mayer, Arnulf, Haist, Maximilian, Loquai, Carmen, Grabbe, Stephan, Rapp, Matthias, Roth, Wilfried, Vaupel, Peter, Schmidberger, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763902/
https://www.ncbi.nlm.nih.gov/pubmed/33322215
http://dx.doi.org/10.3390/cancers12123753