A Limited and Diverse Set of Suppressor Mutations Restore Function to INX-8 Mutant Hemichannels in the Caenorhabditis elegans Somatic Gonad

In Caenorhabditis elegans, gap junctions couple cells of the somatic gonad with the germline to support germ cell proliferation and gametogenesis. A strong loss-of-function mutation (T239I) affects the second extracellular loop (EL2) of the somatic INX-8 hemichannel subunit. These mutant hemichannel...

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Detalles Bibliográficos
Autores principales: Starich, Todd, Greenstein, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763923/
https://www.ncbi.nlm.nih.gov/pubmed/33321846
http://dx.doi.org/10.3390/biom10121655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763923/
https://www.ncbi.nlm.nih.gov/pubmed/33321846
http://dx.doi.org/10.3390/biom10121655

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