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Artesunate Impairs Growth in Cisplatin-Resistant Bladder Cancer Cells by Cell Cycle Arrest, Apoptosis and Autophagy Induction

Cisplatin, which induces DNA damage, is standard chemotherapy for advanced bladder cancer (BCa). However, efficacy is limited due to resistance development. Since artesunate (ART), a derivative of artemisinin originating from Traditional Chinese Medicine, has been shown to exhibit anti-tumor activit...

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Detalles Bibliográficos
Autores principales: Zhao, Fuguang, Vakhrusheva, Olesya, Markowitsch, Sascha D., Slade, Kimberly S., Tsaur, Igor, Cinatl, Jindrich, Michaelis, Martin, Efferth, Thomas, Haferkamp, Axel, Juengel, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763932/
https://www.ncbi.nlm.nih.gov/pubmed/33316936
http://dx.doi.org/10.3390/cells9122643