New Multifunctional Agents Based on Conjugates of 4-Amino-2,3-polymethylenequinoline and Butylated Hydroxytoluene for Alzheimer’s Disease Treatment

New hybrids of 4-amino-2,3-polymethylenequinoline with different sizes of the aliphatic ring linked to butylated hydroxytoluene (BHT) by enaminoalkyl (7) or aminoalkyl (8) spacers were synthesized as potential multifunctional agents for Alzheimer’s disease (AD) treatment. All compounds were potent i...

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Detalles Bibliográficos
Autores principales: Makhaeva, Galina F., Kovaleva, Nadezhda V., Rudakova, Elena V., Boltneva, Natalia P., Lushchekina, Sofya V., Faingold, Irina I., Poletaeva, Darya A., Soldatova, Yuliya V., Kotelnikova, Raisa A., Serkov, Igor V., Ustinov, Anatoly K., Proshin, Alexey N., Radchenko, Eugene V., Palyulin, Vladimir A., Richardson, Rudy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763995/
https://www.ncbi.nlm.nih.gov/pubmed/33322783
http://dx.doi.org/10.3390/molecules25245891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763995/
https://www.ncbi.nlm.nih.gov/pubmed/33322783
http://dx.doi.org/10.3390/molecules25245891

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