Saturated Fatty Acids Promote GDF15 Expression in Human Macrophages through the PERK/eIF2/CHOP Signaling Pathway

Growth differentiation factor-15 (GDF-15) and its receptor GFRAL are both involved in the development of obesity and insulin resistance. Plasmatic GDF-15 level increases with obesity and is positively associated with disease progression. Despite macrophages have been recently suggested as a key sour...

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Detalles Bibliográficos
Autores principales: L’homme, Laurent, Sermikli, Benan Pelin, Staels, Bart, Piette, Jacques, Legrand-Poels, Sylvie, Dombrowicz, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764024/
https://www.ncbi.nlm.nih.gov/pubmed/33302552
http://dx.doi.org/10.3390/nu12123771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764024/
https://www.ncbi.nlm.nih.gov/pubmed/33302552
http://dx.doi.org/10.3390/nu12123771

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