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Establishment of an Immunocompetent Metastasis Rat Model with Hepatocyte Cancer Stem Cells

SIMPLE SUMMARY: Cancer stem cells (CSCs) are considered responsible for the maintenance, metastasis, and recurrence of various tumors. Here, we isolated a novel CSCs, TW-1, which can self-renew, differentiate and resistant to sorafenib. We also established novel orthotopic and metastasis models in i...

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Detalles Bibliográficos
Autores principales: Wu, Semon, Tseng, I-Chieh, Huang, Wen-Cheng, Su, Cheng-Wen, Lai, Yu-Heng, Lin, Che, Lee, Alan Yueh-Luen, Kuo, Chan-Yen, Su, Li-Yu, Lee, Ming-Cheng, Hsu, Te-Cheng, Yu, Chun-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764036/
https://www.ncbi.nlm.nih.gov/pubmed/33322441
http://dx.doi.org/10.3390/cancers12123721