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The Specificity of Downstream Signaling for A(1) and A(2A)R Does Not Depend on the C-Terminus, Despite the Importance of This Domain in Downstream Signaling Strength

Recent efforts to determine the high-resolution crystal structures for the adenosine receptors (A(1)R and A(2A)R) have utilized modifications to the native receptors in order to facilitate receptor crystallization and structure determination. One common modification is a truncation of the unstructur...

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Detalles Bibliográficos
Autores principales: Jain, Abhinav R., McGraw, Claire, Robinson, Anne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764039/
https://www.ncbi.nlm.nih.gov/pubmed/33322210
http://dx.doi.org/10.3390/biomedicines8120603