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The Specificity of Downstream Signaling for A(1) and A(2A)R Does Not Depend on the C-Terminus, Despite the Importance of This Domain in Downstream Signaling Strength
Recent efforts to determine the high-resolution crystal structures for the adenosine receptors (A(1)R and A(2A)R) have utilized modifications to the native receptors in order to facilitate receptor crystallization and structure determination. One common modification is a truncation of the unstructur...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764039/ https://www.ncbi.nlm.nih.gov/pubmed/33322210 http://dx.doi.org/10.3390/biomedicines8120603 |