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Dysregulated Interferon Response Underlying Severe COVID-19

Innate immune interferons (IFNs), including type I and III IFNs, constitute critical antiviral mechanisms. Recent studies reveal that IFN dysregulation is key to determine COVID-19 pathogenesis. Effective IFN stimulation or prophylactic administration of IFNs at the early stage prior to severe COVID...

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Detalles Bibliográficos
Autores principales: Lopez, LeAnn, Sang, Peter C., Tian, Yun, Sang, Yongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764122/
https://www.ncbi.nlm.nih.gov/pubmed/33322160
http://dx.doi.org/10.3390/v12121433